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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2002-4-30
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pubmed:abstractText |
We determined the sequence of the intergenic spacer (IGS) 1 region, which is located between the 26S and 5S rRNA genes, in 25 species of the genus TRICHOSPORON: IGS 1 sequences varied in length from 195 to 719 bp. Comparative sequence analysis suggested that the divergence of IGS 1 sequences has been greater than that of the internal transcribed spacer regions. We also identified five genotypes of T. asahii, which is a major causative agent of deep-seated trichosporonosis, based on the IGS 1 sequences of 43 strains. Most of the isolates that originated in Japan were of genotype 1, whereas the American isolates were of genotype 3 or 5. Our results suggest that analysis of IGS regions provides a powerful method to distinguish between phylogenetically closely related species and that a geographic substructure may exist among T. asahii clinical isolates.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-10325335,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-10325360,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-10628823,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-10790115,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-10834993,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-11050543,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-11249024,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-11791669,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-7615757,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-7935589,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-7984417,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-8176723,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-9061585,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-9114410,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-9425241,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980969-9850420
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Fungal,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Ribosomal,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Ribosomal,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Ribosomal, 5S,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, ribosomal, 26S
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0095-1137
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1826-30
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:11980969-Animals,
pubmed-meshheading:11980969-DNA, Fungal,
pubmed-meshheading:11980969-DNA, Ribosomal,
pubmed-meshheading:11980969-Humans,
pubmed-meshheading:11980969-Introns,
pubmed-meshheading:11980969-Mycoses,
pubmed-meshheading:11980969-Phylogeny,
pubmed-meshheading:11980969-RNA, Ribosomal,
pubmed-meshheading:11980969-RNA, Ribosomal, 5S,
pubmed-meshheading:11980969-Sequence Alignment,
pubmed-meshheading:11980969-Trichosporon
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pubmed:year |
2002
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pubmed:articleTitle |
Sequence analysis of the ribosomal DNA intergenic spacer 1 regions of Trichosporon species.
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pubmed:affiliation |
Department of Microbiology, Meiji Pharmaceutical University, Kiyose, Tokyo 204-8588, Japan. sugita@my-pharm.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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