Linked Life Data

11980944

Source:http://linkedlifedata.com/resource/pubmed/id/11980944

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2002-4-30
pubmed:abstractText
A commercially prepared frozen broth microdilution panel (Trek Diagnostic Systems, Westlake, Ohio) was compared with a reference microdilution panel for antifungal susceptibility testing of two quality control (QC) strains and 99 clinical isolates of Candida spp. The antifungal agents tested included amphotericin B, flucytosine, fluconazole, itraconazole, posaconazole, ravuconazole, and voriconazole. Microdilution testing was performed according to NCCLS recommendations. MIC endpoints were read visually after 48 h of incubation and were assessed independently for each microdilution panel. The MICs for the QC strains were within published limits for both the reference and Trek microdilution panels. Discrepancies among MIC endpoints of no more than 2 dilutions were used to calculate the percent agreement. Acceptable levels of agreement between the Trek and reference panels were observed for all antifungal agents tested against the 99 clinical isolates. The overall agreement for each antifungal agent ranged from 96% for ravuconazole to 100% for amphotericin B. The Trek microdilution panel appears to be a viable alternative to frozen microdilution panels prepared in-house.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/11980944-10770728, http://linkedlifedata.com/resource/pubmed/commentcorrection/11980944-10970403, http://linkedlifedata.com/resource/pubmed/commentcorrection/11980944-11501985, http://linkedlifedata.com/resource/pubmed/commentcorrection/11980944-11526159, http://linkedlifedata.com/resource/pubmed/commentcorrection/11980944-11557481, http://linkedlifedata.com/resource/pubmed/commentcorrection/11980944-11585779, http://linkedlifedata.com/resource/pubmed/commentcorrection/11980944-7615712, http://linkedlifedata.com/resource/pubmed/commentcorrection/11980944-7956018, http://linkedlifedata.com/resource/pubmed/commentcorrection/11980944-8882893, http://linkedlifedata.com/resource/pubmed/commentcorrection/11980944-9705401, http://linkedlifedata.com/resource/pubmed/commentcorrection/11980944-9835520
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0095-1137
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1694-7
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Clinical evaluation of a frozen commercially prepared microdilution panel for antifungal susceptibility testing of seven antifungal agents, including the new triazoles posaconazole, ravuconazole, and voriconazole.
pubmed:affiliation
Medical Microbiology Division, C606 GH, Department of Pathology, University of Iowa College of Medicine, Iowa City, IA 52242, USA. michael-pfaller@uiowa.edu
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't