Linked Life Data

1197903

Source:http://linkedlifedata.com/resource/pubmed/id/1197903

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1976-2-27
pubmed:abstractText
Magnesium causes a marked decrease in the initial rates of respiration-supported calcium uptake by isolated heart mitochondria. Differential responses of mitochondrial respiration and cytochrome b redox states in the presence and absence of magnesium indicate that with magnesium present, heart mitochondria retain the ability to phosphorylate ADP after calcium uptake. Electron microscopy of the isolated mitochondria after calcium accumulation revealed markedly different crystal structures within the matrix space depending on the presence or absence of magnesium. The results suggest a "protective" effect of magnesium on the phosphorylating mechanism of mitochondria during active calcium uptake. Further, magnesium appears to determine the type of crystal structure formation within the intramitochondrial compartment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0363-5872
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
85-93
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Pathological accumulation of calcium by mitochondria: modulation by magnesium.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.