Linked Life Data

11978054

Source:http://linkedlifedata.com/resource/pubmed/id/11978054

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2002-4-29
pubmed:abstractText
The placental transport of amino acids which is nutritionally important is the net entry rate into the fetal circulation (the umbilical uptake). This entry rate is a function of transport across cell membranes, the effect of competition among amino acids for transport, particularly across the fetal surface of the trophoblast, and their metabolism and interconversion within the placenta. The result of these different interactive fluxes is that the relationship between maternal concentration and fetal supply of an amino acid differs for each amino acid. For some amino acids there are relatively large bidirectional fluxes at both the fetal and maternal surfaces of the placenta. These fluxes can be measured in vivo utilizing stable isotope methodology. There is an important interorgan exchange of amino acids between the placenta and fetal liver. This exchange is, at least in part, a function of the absence of gluconeogenesis in the fetal liver. Both glutamate and serine, which are released from the fetal liver, are taken up by the placenta from the fetal circulation and metabolized within the placenta.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0143-4004
pubmed:author
pubmed:copyrightInfo
Copyright 2002 IFPA and Elsevier Science Ltd.
pubmed:issnType
Print
pubmed:volume
23 Suppl A
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S3-8
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
In vivo characteristics of placental amino acid transport and metabolism in ovine pregnancy--a review.
pubmed:affiliation
Division of Perinatal Medicine, Department of Pediatrics, University of Colorado, Fitzsimons, Bldg 260, Denver, CO 80045-0508, USA. Fred.Battaglia@UCHSC.edu
pubmed:publicationType
Journal Article, Review