Source:http://linkedlifedata.com/resource/pubmed/id/11977370
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2002-4-29
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pubmed:abstractText |
The investigations were carried out on thyroids of white Wistar rats which were given Metizol for 3 days, 3 and 6 weeks at the dose of 1 mg/kg of b.m. for 24 hrs. The samples were stained with hematoxylin and eosin and by the PAS method. The following changes were observed: 1. Three-day administration of Metizol resulted in the decrease in the quantity of colloid; the secretory epithelium became uniform--i.e. cubic; the quantity of the interfollicular tissue increased. 2. Three-week administration of Metizol resulted in appearing of colloid stained differently than in the control group; secretory epithelium cells were of different height (cubic and cylindrical), a considerate congestion of the gland was visible, the quantity of the interfollicular tissue increased. 3. After 6 weeks of Metizol administration the morphological picture of the thyroid became similar to that of the control group.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0066-2240
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
85-8
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pubmed:dateRevised |
2009-6-5
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pubmed:meshHeading |
pubmed-meshheading:11977370-Animals,
pubmed-meshheading:11977370-Antithyroid Agents,
pubmed-meshheading:11977370-Colloids,
pubmed-meshheading:11977370-Drug Administration Schedule,
pubmed-meshheading:11977370-Epithelium,
pubmed-meshheading:11977370-Male,
pubmed-meshheading:11977370-Methimazole,
pubmed-meshheading:11977370-Rats,
pubmed-meshheading:11977370-Rats, Wistar,
pubmed-meshheading:11977370-Thyroid Gland
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pubmed:year |
2001
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pubmed:articleTitle |
Histological examination of the thyroid after experimental administration of Metizol.
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pubmed:affiliation |
Department of Institute of Histology and Embryology, Medical University of Lublin.
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pubmed:publicationType |
Journal Article
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