Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2002-4-26
pubmed:abstractText
Unstable angina pectoris and non-Q-wave myocardial infarction are clinical syndromes that share many pathophysiologic and clinical features. In the spectrum of coronary artery disease, these syndromes lie between chronic stable angina and Q-wave myocardial infarction. Although both conditions are associated with significant morbidity and mortality, patients presenting with these syndromes can be further risk stratified into higher and lower risk based on a number of readily available clinical features and biochemical parameters. Such risk stratification can allow for more tailored treatment and better resource allocation. Although routine early coronary angiography and revascularization has not been shown to be superior to conservative management, certain high-risk patients may benefit from a more aggressive strategy. Medical therapy with the use of antiplatelet, anticoagulant, and antiischemic agents remains the cornerstone of emergent treatment for patients presenting with these syndromes. The recent demonstration of a reduction in both morbidity and mortality with the glycoprotein IIb/IIIa antagonists has further expanded the armamentarium of available agents. Following initial stabilization, risk stratification with stress testing can help identify patients with a large residual ischemic burden who may benefit from coronary angiography with revascularization if feasible.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1521-737X
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
116-30
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed-meshheading:11975780-Age Factors, pubmed-meshheading:11975780-Angina, Unstable, pubmed-meshheading:11975780-Biological Markers, pubmed-meshheading:11975780-Cardiovascular Agents, pubmed-meshheading:11975780-Cardiovascular Surgical Procedures, pubmed-meshheading:11975780-Coronary Angiography, pubmed-meshheading:11975780-Creatine Kinase, pubmed-meshheading:11975780-Creatine Kinase, MB Form, pubmed-meshheading:11975780-Electrocardiography, pubmed-meshheading:11975780-Europe, pubmed-meshheading:11975780-Humans, pubmed-meshheading:11975780-Isoenzymes, pubmed-meshheading:11975780-Myocardial Infarction, pubmed-meshheading:11975780-Risk Factors, pubmed-meshheading:11975780-Treatment Outcome, pubmed-meshheading:11975780-Troponin, pubmed-meshheading:11975780-United States, pubmed-meshheading:11975780-Ventricular Function, Left
pubmed:articleTitle
Unstable angina pectoris and non-Q-wave myocardial infarction.
pubmed:affiliation
Department of Medicine, Division of Cardiology, Bronx VA Medical Center, New York 10468, USA.
pubmed:publicationType
Journal Article, Review