Source:http://linkedlifedata.com/resource/pubmed/id/11973165
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
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| pubmed:dateCreated |
2002-4-25
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| pubmed:abstractText |
Outcome after cardiac surgery varies depending on complication type. We therefore sought to determine the association between complication type, mortality, and length of stay in a large series of patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Multivariate logistic regression was used to test for differences between complication types in mortality and prolonged length of stay (>10 days) while controlling for preoperative and intraoperative risk factors. In 2609 consecutive cardiac surgical patients requiring CPB, the mortality rate was 3.6%; 36.5% had one or more complications, and 15.7% experienced an adverse outcome (death or prolonged length of stay). Multivariate logistic regression demonstrated that complication type was significantly associated with adverse outcome (P < 0.001) independent of Parsonnet score and CPB time (c-index = 0.80). The development of noncardiac complications only (Group NC) and cardiac complications with other organ involvement (Group B) significantly increased mortality and hospital and intensive care unit length of stay (P < 0.001) when compared with cardiac complications only (Group C). The incidences of adverse outcome in Groups C, NC, and B were 15%, 43%, and 67%, respectively; the mortality rates were 3%, 7%, and 20%, respectively. All these intergroup comparisons were significantly different (adjusted P < 0.05). Complications involving organs other than the heart appear to be more deleterious than cardiac complications alone, underscoring the need for strategies to reduce noncardiac complications. IMPLICATIONS: Complications, particularly when they involve organs other than just the heart, increase mortality and prolong the length of hospital stay after heart surgery, independent of a patient's preoperative risk factors and the duration of cardiopulmonary bypass. Strategies aimed at preventing damage to other organs during cardiac surgery need to be improved.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:status |
MEDLINE
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| pubmed:month |
May
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| pubmed:issn |
0003-2999
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
94
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
1072-8
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| pubmed:dateRevised |
2007-1-25
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| pubmed:meshHeading |
pubmed-meshheading:11973165-Adult,
pubmed-meshheading:11973165-Aged,
pubmed-meshheading:11973165-Cardiac Surgical Procedures,
pubmed-meshheading:11973165-Cardiopulmonary Bypass,
pubmed-meshheading:11973165-Female,
pubmed-meshheading:11973165-Humans,
pubmed-meshheading:11973165-Length of Stay,
pubmed-meshheading:11973165-Male,
pubmed-meshheading:11973165-Middle Aged,
pubmed-meshheading:11973165-Postoperative Complications,
pubmed-meshheading:11973165-Time Factors
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| pubmed:year |
2002
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| pubmed:articleTitle |
The association of complication type with mortality and prolonged stay after cardiac surgery with cardiopulmonary bypass.
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| pubmed:affiliation |
Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA. welsb001@duke.edu
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| pubmed:publicationType |
Journal Article
|