Source:http://linkedlifedata.com/resource/pubmed/id/11970873
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2002-4-23
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pubmed:abstractText |
The viral Nef protein is important for the progression of the human and simian immunodeficiency virus (HIV/SIV) infection. So far, experimental evidence has suggested that Nef enhances viral replication and infectivity through a combination of different effects. Recent insights, however, indicate that its functions are more complex than previously anticipated. By targeting the T cell receptor, Nef may not only prime viral replication but, more importantly, ensure viral survival through distinct mechanisms of immune evasion and antiapoptosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1074-7613
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
493-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11970873-Animals,
pubmed-meshheading:11970873-Apoptosis,
pubmed-meshheading:11970873-Gene Products, nef,
pubmed-meshheading:11970873-HIV,
pubmed-meshheading:11970873-Humans,
pubmed-meshheading:11970873-Receptors, Antigen, T-Cell,
pubmed-meshheading:11970873-T-Lymphocytes,
pubmed-meshheading:11970873-Virus Replication,
pubmed-meshheading:11970873-nef Gene Products, Human Immunodeficiency Virus
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pubmed:year |
2002
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pubmed:articleTitle |
Live and let die: Nef functions beyond HIV replication.
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pubmed:affiliation |
Department of Virology, University of Heidelberg, D-69120 Heidelberg, Germany.
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pubmed:publicationType |
Journal Article,
Review
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