Linked Life Data

11968850

Source:http://linkedlifedata.com/resource/pubmed/id/11968850

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2002-4-23
pubmed:abstractText
More than 2 decades have past since the first transgenic mouse was created. In this review we will focus on recent technologies in the field of mouse genetic engineering and on its application to bioindustry. The most important milestone in this field was the invention of the gene targeting technique. Recent improvement of this technique to conditional gene targeting together with the Cre/IoxP system further encouraged the generation of mutant mice. It is obvious that there will be a great demand for some mutant mice as experimental models of human disease or as resources of experimental material for basis biological research. Thus, creation of such mice would be a rewarding challenge for a biological enterprise.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0367-6102
pubmed:author
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
151-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
[Genetically engineered mice and its application to bioindustry].
pubmed:affiliation
Division of Immunoregulation, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.
pubmed:publicationType
Journal Article, English Abstract, Review