Linked Life Data

11967920

Source:http://linkedlifedata.com/resource/pubmed/id/11967920

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2002-5-23
pubmed:abstractText
Transcription factor AP-2alpha has been implicated as a cell-type-specific regulator of gene expression during vertebrate embryogenesis based on its expression pattern in neural crest cells, ectoderm, and the nervous system in mouse, chick, and frog embryos. AP-2alpha is prominently expressed in cranial neural crest cells, a population of cells migrating from the lateral margins of the neural folds during closure of the neural tube in E (embryonic day of development) 8-9 mouse embryos. Homozygous AP-2alpha mutant mice die perinatally with cranio-abdominoschisis, full facial clefting, and defects in cranial ganglia and sensory organs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0040-3709
pubmed:author
pubmed:copyrightInfo
Copyright 2002 Wiley-Liss, Inc.
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
213-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Exencephaly in a subset of animals heterozygous for AP-2alpha mutation.
pubmed:affiliation
Forschungszentrum Karlsruhe, ITG, Institute for Toxicology and Genetics, Leopoldshafen, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't