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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2002-4-22
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pubmed:abstractText |
Previous studies have identified regions within alpha3(IV) collagen in human antiglomerular basement membrane (anti-GBM) disease, however, information pertaining to the nature of the pathogenic human autoantibodies has been limited by a lack of a relevant disease model. Availability of engineered mice that produce antibodies (that is, XenoMouse II strains) provides an ideal opportunity to examine the human antibody response.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1666-73
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11967016-Animals,
pubmed-meshheading:11967016-Anti-Glomerular Basement Membrane Disease,
pubmed-meshheading:11967016-Antibodies,
pubmed-meshheading:11967016-Antibodies, Monoclonal,
pubmed-meshheading:11967016-Antibody Specificity,
pubmed-meshheading:11967016-Autoantibodies,
pubmed-meshheading:11967016-Autoantigens,
pubmed-meshheading:11967016-Collagen Type IV,
pubmed-meshheading:11967016-Disease Models, Animal,
pubmed-meshheading:11967016-Humans,
pubmed-meshheading:11967016-Mice,
pubmed-meshheading:11967016-Mice, Transgenic
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pubmed:year |
2002
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pubmed:articleTitle |
Human antiglomerular basement membrane autoantibody disease in XenoMouse II.
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pubmed:affiliation |
Penn Center for Molecular Studies of Kidney Diseases, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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