11966948

Source:http://linkedlifedata.com/resource/pubmed/id/11966948

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0003595, umls-concept:C0012655, umls-concept:C0014442, umls-concept:C0149521, umls-concept:C1623038, umls-concept:C1882417, umls-concept:C2825097
pubmed:issue	2
pubmed:dateCreated	2002-4-22
pubmed:abstractText	Susceptibility to organ damage induced by alcohol may be due to inherited variation (polymorphism) in ethanol-metabolizing enzymes, or to polymorphisms affecting free radical or lipid metabolism mediated by enzymes such as glutathione S-transferases and apolipoprotein E. The aim was to compare the genotype frequencies of alcohol dehydrogenase-2 (ADH2), ADH3, aldehyde dehydrogenase-2 (ALDH2), cytochrome P450-2E1 (CYP2E1), glutathione S-transferase-M1 (GSTM1), GSTT1, and apolipoprotein E in patients with alcoholic cirrhosis and alcoholic chronic pancreatitis to those in control groups.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8607909
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Alcohol Dehydrogenase, http://linkedlifedata.com/resource/pubmed/chemical/Aldehyde Dehydrogenase, http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP2E1, http://linkedlifedata.com/resource/pubmed/chemical/Ethanol, http://linkedlifedata.com/resource/pubmed/chemical/Glutathione Transferase, http://linkedlifedata.com/resource/pubmed/chemical/Oxidoreductases
pubmed:status	MEDLINE
pubmed:month	Feb
pubmed:issn	0815-9319
pubmed:author	pubmed-author:ApteMinoti VMV, pubmed-author:ButlerWendy JWJ, pubmed-author:FrenzerAndreasA, pubmed-author:NortonIan DID, pubmed-author:PirolaRomano CRC, pubmed-author:Roberts-ThomsonIan CIC, pubmed-author:RyanPhilipP, pubmed-author:WilsonJeremy SJS
pubmed:issnType	Print
pubmed:volume	17
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	177-82
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:11966948-Adult, pubmed-meshheading:11966948-Alcohol Dehydrogenase, pubmed-meshheading:11966948-Aldehyde Dehydrogenase, pubmed-meshheading:11966948-Apolipoproteins E, pubmed-meshheading:11966948-Case-Control Studies, pubmed-meshheading:11966948-Cytochrome P-450 CYP2E1, pubmed-meshheading:11966948-Ethanol, pubmed-meshheading:11966948-Female, pubmed-meshheading:11966948-Gene Frequency, pubmed-meshheading:11966948-Genetic Predisposition to Disease, pubmed-meshheading:11966948-Genotype, pubmed-meshheading:11966948-Glutathione Transferase, pubmed-meshheading:11966948-Humans, pubmed-meshheading:11966948-Liver Cirrhosis, Alcoholic, pubmed-meshheading:11966948-Male, pubmed-meshheading:11966948-Middle Aged, pubmed-meshheading:11966948-Oxidoreductases, pubmed-meshheading:11966948-Pancreatitis, Alcoholic, pubmed-meshheading:11966948-Polymorphism, Genetic, pubmed-meshheading:11966948-Polymorphism, Restriction Fragment Length
pubmed:year	2002
pubmed:articleTitle	Polymorphism in alcohol-metabolizing enzymes, glutathione S-transferases and apolipoprotein E and susceptibility to alcohol-induced cirrhosis and chronic pancreatitis.
pubmed:affiliation	Department of Gastroenterology, The Queen Elizabeth Hospital, Adelaide, SA, Australia.
pubmed:publicationType	Journal Article