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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
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pubmed:dateCreated |
1976-2-26
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pubmed:abstractText |
The cytotoxic properties of a hetero-antiserum have been used to demonstrate surface antigen(s) common to seven human astrocytomas. This has been designated human astrocytoma-associated antigen (HAAA). Tissue cultures of astrocytomas were prepared. A rabbit antiserum was raised to one of these and its antibody activity on the original tumour cells assayed by dye exclusion cytotoxicity testing. After repeated absorption with associated antigen(s). In a series of absorption experiments, HAAA was detected in six other human astrocytoma cultures, but not found in a series of other human tumours and tissues tested. Homogenates of two original astrocytomas absorbed out HAAA activity in a similar way indicating the presence of the antigen(s) in vivo. The significance of this HAAA is discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0030-2414
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
234-43
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1196582-Antigens, Neoplasm,
pubmed-meshheading:1196582-Astrocytoma,
pubmed-meshheading:1196582-Brain Neoplasms,
pubmed-meshheading:1196582-Cell Membrane,
pubmed-meshheading:1196582-Cross Reactions,
pubmed-meshheading:1196582-Culture Techniques,
pubmed-meshheading:1196582-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:1196582-Humans
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pubmed:year |
1975
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pubmed:articleTitle |
Tumour-associated surface antigen(s) in human astrocytomas.
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pubmed:publicationType |
Journal Article
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