Source:http://linkedlifedata.com/resource/pubmed/id/11965366
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2002-4-19
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pubmed:abstractText |
Development of aminoglycoside-nucleic acid conjugates is presented. Synthesis of a DNA dimer covalently linked to kanamycin and neomycin isothiocyanates has been carried out. The development of such conjugates will help couple the sequence specificity of nucleic acids to the electrostatic/shape complementarity of aminoglycoside antibiotics in binding nucleic acid targets.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
6
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1259-62
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11965366-Aminoglycosides,
pubmed-meshheading:11965366-Anti-Bacterial Agents,
pubmed-meshheading:11965366-Carbohydrate Sequence,
pubmed-meshheading:11965366-DNA,
pubmed-meshheading:11965366-Magnetic Resonance Spectroscopy,
pubmed-meshheading:11965366-Mass Spectrometry,
pubmed-meshheading:11965366-Molecular Sequence Data
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pubmed:year |
2002
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pubmed:articleTitle |
Synthesis of aminoglycoside-DNA conjugates.
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pubmed:affiliation |
Laboratory of Medicinal Chemistry, Department of Chemistry, Clemson University, Clemson, SC 29634, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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