Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2002-4-17
pubmed:abstractText
Sickle cell anemia exhibits significant variations in clinical presentation in different populations despite the homogeneity of the genetic defect which is involved. Genetic modulation of this disease is known but cannot explain alone such observations. Our objectives were to determine the effects of Hb F level, sociocultural and economic factors on disease severity in Dakar. Sixty homozygous sickle cell patients were followed up between october 1996 and April 1998 during which period the severity of the disease was assessed and a "severity index" was calculated for each patient. The factors which were identified with proved benefit were: Hb F > 15%, a high socioeconomic level, a good understanding of the disease, at least 4 medical visits per year. These results allow us to identify some potential targets to improve preventive and curative care of this disease.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0049-1101
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
171-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
[Homozygous drepanocytosis in Dakar: effect of the hemoglobin F level, and sociocultural and economic factors].
pubmed:affiliation
Travail du Service d'Hématologie et d'Immunologie, CNTS BP5002, Dakar, Fann.
pubmed:publicationType
Journal Article, English Abstract