Linked Life Data

11962655

Source:http://linkedlifedata.com/resource/pubmed/id/11962655

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2002-4-18
pubmed:abstractText
In vitro bioactivity of composites of poly(epsilon-caprolactone-co-DL-lactide) P(CL/DL-LA) containing different amounts (40, 60 and 70 wt%) of bioactive glass, S53P4, was evaluated. Two ranges of granule size of bioactive glass (< 45 microm and 90-315 microm) were blended with P(CL/DL-LA) copolymer in a batch mixer. The composites were characterised by dynamic mechanical thermal analysis. The molecular weight and the melting temperature of the copolymer matrix were adjusted to enable the application of the composite material by injection below 50 degrees C. Formation of Ca-P deposition on the surface of the composites after dissolution in simulated body fluid at 37 degrees C was recorded by scanning electron microscopy. Degradation of the composite material was measured by water absorption and changes in the average molecular weights as a function of the dissolution time. In vitro bioactivity was found to be dependent on the weight fraction and granule size range of the bioactive glass used. The presence of the bioactive filler also accelerated the degradation compared with the neat polymer sample.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0142-9612
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2143-50
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
In vitro evaluation of poly(epsilon-caprolactone-co-DL-lactide)/ bioactive glass composites.
pubmed:affiliation
Department of Chemical Technology, Polymer Technology, Helsinki University of Technology, Espoo, Finland. seppala@polte.hut.fi
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't