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pubmed-article:11948142pubmed:abstractTextThe tumor suppressor gene p16INK4A is inactivated frequently in a large number of human cancers, and many investigators have attempted to restore the function of p16 using the p16 wild-type gene and viral vectors. In this study, we treated the tumor-bearing animals with the p16-derived synthetic peptide coupled with the Antennapedia carrier sequence, which we designated as Trojan p16 peptide.lld:pubmed
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pubmed-article:11948142pubmed:articleTitleTrojan p16 peptide suppresses pancreatic cancer growth and prolongs survival in mice.lld:pubmed
pubmed-article:11948142pubmed:affiliationDepartment of Surgery and Surgical Basic Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan. hoso@h8.dion.ne.jplld:pubmed
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