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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2002-4-11
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pubmed:abstractText |
The tumor suppressor gene p16INK4A is inactivated frequently in a large number of human cancers, and many investigators have attempted to restore the function of p16 using the p16 wild-type gene and viral vectors. In this study, we treated the tumor-bearing animals with the p16-derived synthetic peptide coupled with the Antennapedia carrier sequence, which we designated as Trojan p16 peptide.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1271-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11948142-Amino Acid Sequence,
pubmed-meshheading:11948142-Animals,
pubmed-meshheading:11948142-Blood Cell Count,
pubmed-meshheading:11948142-Body Weight,
pubmed-meshheading:11948142-Cell Division,
pubmed-meshheading:11948142-Cyclin-Dependent Kinase Inhibitor p16,
pubmed-meshheading:11948142-Dose-Response Relationship, Drug,
pubmed-meshheading:11948142-Humans,
pubmed-meshheading:11948142-Male,
pubmed-meshheading:11948142-Mice,
pubmed-meshheading:11948142-Mice, Inbred BALB C,
pubmed-meshheading:11948142-Mice, Nude,
pubmed-meshheading:11948142-Molecular Sequence Data,
pubmed-meshheading:11948142-Neoplasm Transplantation,
pubmed-meshheading:11948142-Pancreatic Neoplasms,
pubmed-meshheading:11948142-Peptide Fragments,
pubmed-meshheading:11948142-Survival Analysis,
pubmed-meshheading:11948142-Survival Rate,
pubmed-meshheading:11948142-Tumor Cells, Cultured,
pubmed-meshheading:11948142-Xenograft Model Antitumor Assays
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pubmed:year |
2002
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pubmed:articleTitle |
Trojan p16 peptide suppresses pancreatic cancer growth and prolongs survival in mice.
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pubmed:affiliation |
Department of Surgery and Surgical Basic Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan. hoso@h8.dion.ne.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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