rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2002-4-9
|
pubmed:abstractText |
Forskolin, a direct activator of adenylate cyclase, can relax airway smooth muscle, similar to other agents that increase intracellular cyclic adenine monophosphate. However, the potential usefulness of forskolin in treating bronchospasm is limited by its poor water solubility. Colforsin daropate is a novel and potent water-soluble forskolin derivative. No clinical data have been published on the bronchorelaxant effects of this drug. The aim of this study was to investigate whether intravenous colforsin daropate prevents thiamylal-fentanyl-induced bronchoconstriction.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0090-3493
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
820-6
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:11940752-Adult,
pubmed-meshheading:11940752-Airway Resistance,
pubmed-meshheading:11940752-Anesthesia, Intravenous,
pubmed-meshheading:11940752-Anesthetics, Intravenous,
pubmed-meshheading:11940752-Bronchoconstriction,
pubmed-meshheading:11940752-Bronchodilator Agents,
pubmed-meshheading:11940752-Female,
pubmed-meshheading:11940752-Fentanyl,
pubmed-meshheading:11940752-Forskolin,
pubmed-meshheading:11940752-Hemodynamics,
pubmed-meshheading:11940752-Humans,
pubmed-meshheading:11940752-Infusions, Intravenous,
pubmed-meshheading:11940752-Lung Compliance,
pubmed-meshheading:11940752-Male,
pubmed-meshheading:11940752-Prospective Studies,
pubmed-meshheading:11940752-Thiamylal
|
pubmed:year |
2002
|
pubmed:articleTitle |
Intravenous colforsin daropate, a water-soluble forskolin derivative, prevents thiamylal-fentanyl-induced bronchoconstriction in humans.
|
pubmed:affiliation |
Department of Anesthesia, Chiba Hokusoh Hospital, Chiba, Japan. HFB01245@nifty.com
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|