Linked Life Data

11940106

Source:http://linkedlifedata.com/resource/pubmed/id/11940106

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2002-4-9
pubmed:abstractText
In this study, we show that inhibitors of the glucose-6-phosphatase (G-6-Pase) catalytic protein could be an alternative approach to the recent G-6-Pase T1-translocase inhibitors to target this enzyme for the treatment of type 2 diabetes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1462-8902
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
96-105
pubmed:dateRevised
2009-11-3
pubmed:meshHeading
pubmed-meshheading:11940106-Animals, pubmed-meshheading:11940106-Benzophenones, pubmed-meshheading:11940106-Binding, Competitive, pubmed-meshheading:11940106-Catalysis, pubmed-meshheading:11940106-Drug Design, pubmed-meshheading:11940106-Enzyme Inhibitors, pubmed-meshheading:11940106-Glucose, pubmed-meshheading:11940106-Glucose-6-Phosphatase, pubmed-meshheading:11940106-Glucosephosphate Dehydrogenase, pubmed-meshheading:11940106-Glycogen, pubmed-meshheading:11940106-Hepatocytes, pubmed-meshheading:11940106-Kinetics, pubmed-meshheading:11940106-Lactates, pubmed-meshheading:11940106-Male, pubmed-meshheading:11940106-Microsomes, Liver, pubmed-meshheading:11940106-Pyridines, pubmed-meshheading:11940106-Rats, pubmed-meshheading:11940106-Rats, Sprague-Dawley, pubmed-meshheading:11940106-Structure-Activity Relationship, pubmed-meshheading:11940106-Swine
pubmed:year
2002
pubmed:articleTitle
Identification of two novel and potent competitive inhibitors of the glucose-6-phosphatase catalytic protein.
pubmed:affiliation
Department of Diabetes Biochemistry and Metabolism, Novo Nordisk A/S, DK-2760 Måløv, Denmark.
pubmed:publicationType
Journal Article