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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2002-4-3
pubmed:abstractText
We present a method for visually and quantitatively assessing the presence of structure in clustered data. The method exploits measurements of the stability of clustering solutions obtained by perturbing the data set. Stability is characterized by the distribution of pairwise similarities between clusterings obtained from sub samples of the data. High pairwise similarities indicate a stable clustering pattern. The method can be used with any clustering algorithm; it provides a means of rationally defining an optimum number of clusters, and can also detect the lack of structure in data. We show results on artificial and microarray data using a hierarchical clustering algorithm.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1793-5091
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6-17
pubmed:dateRevised
2007-9-12
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
A stability based method for discovering structure in clustered data.
pubmed:affiliation
BioWulf Technologies LLC, 2030 Addison st. Suite 102, Berkeley, CA 94704, USA.
pubmed:publicationType
Journal Article