Linked Life Data

11925004

Source:http://linkedlifedata.com/resource/pubmed/id/11925004

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2002-4-1
pubmed:abstractText
We examined whether lateral spread of adaptation can be observed in the electroretinogram in humans. Specifically, we tested whether the luminance level of a surrounding, nonmodulated annulus affects the multifocal electroretinogram (ERG) response of a modulated central area. Multifocal electroretinograms were recorded in response to an array of 37 unscaled hexagons subtending a retinal area of 38 deg x 35 deg. Responses were recorded in six control subjects. In the first series of experiments, only the center hexagon was modulated, while the surrounding 36 hexagons were held constant at either 0.45, 172, or 340 cd/m2. In a subsequent series of control experiments, modulation depth of the center hexagon was varied and the proximity of the surrounding hexagon systematically altered. For the center-modulated condition, response amplitude and implicit time for the first-order kernel response significantly decreased as a function of increasing surround luminance. Control experiments demonstrated that the effect of the surround illumination was not due to scattered light but was influenced by the proximity of the surrounding annulus. These results demonstrate that lateral adaptation influences can be measured using the multifocal ERG.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0952-5238
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
687-94
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Lateral spread of adaptation as measured with the multifocal electroretinogram.
pubmed:affiliation
Department of Ophthalmology, New York University School of Medicine, New York 10016, USA. whs4@nyu.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't