rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2002-3-28
|
pubmed:abstractText |
Elevated ErbB2 expression and gene amplification have been shown to be associated with poor prognosis in many cancers. Recently, it has been demonstrated that overexpression of ErbB2 protein in osteosarcoma is associated with the presence of pulmonary metastasis and decreased survival. By contrast, a previous study showed that the expression of ErbB2 declines in individual osteosarcomas as they become metastatic. In the current study, the authors determined the relation between ErbB2 status and outcome in a large number of selected patients with high-grade osteosarcoma.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0008-543X
|
pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2002 American Cancer Society.
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
94
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1397-404
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:11920494-Adolescent,
pubmed-meshheading:11920494-Adult,
pubmed-meshheading:11920494-Bone Neoplasms,
pubmed-meshheading:11920494-Child,
pubmed-meshheading:11920494-Disease-Free Survival,
pubmed-meshheading:11920494-Female,
pubmed-meshheading:11920494-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:11920494-Genes, erbB-2,
pubmed-meshheading:11920494-Humans,
pubmed-meshheading:11920494-Immunohistochemistry,
pubmed-meshheading:11920494-Male,
pubmed-meshheading:11920494-Middle Aged,
pubmed-meshheading:11920494-Neoplasm Metastasis,
pubmed-meshheading:11920494-Osteosarcoma,
pubmed-meshheading:11920494-Prognosis,
pubmed-meshheading:11920494-Receptor, erbB-2
|
pubmed:year |
2002
|
pubmed:articleTitle |
ErbB2 expression is correlated with increased survival of patients with osteosarcoma.
|
pubmed:affiliation |
Department of Orthopaedic Surgery, Sapporo Medical University, Sapporo, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|