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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2002-3-28
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pubmed:abstractText |
One hundred-and-six adult cases of acute lymphoblastic leukemia were prospectively investigated using a highly sensitive interphase fluorescence in situ hybridization assay which utilizes DNA probes that detect a double BCR/ABL fusion signal (D-FISH) in cells carrying the t(9;22) to evaluate the reliability and specificity of this method for the detection of the Ph translocation. The results were compared with those obtained in the same cases by conventional cytogenetics and by reverse-transcription polymerase chain reaction.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1466-4860
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pubmed:author |
pubmed-author:AnninoLL,
pubmed-author:CastoldiG LGL,
pubmed-author:CilloniDD,
pubmed-author:CiminoGG,
pubmed-author:De CuiaM RMR,
pubmed-author:Di RaimondoFF,
pubmed-author:FryGG,
pubmed-author:GIMEMA study group,
pubmed-author:KüngDD,
pubmed-author:ManciniMM,
pubmed-author:MecucciCC,
pubmed-author:NanniMM,
pubmed-author:SantoroAA,
pubmed-author:SirletoPP,
pubmed-author:SpecchiaGG,
pubmed-author:TedeschiAA,
pubmed-author:TodeschiniGG
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pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
54-60
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11920234-Adolescent,
pubmed-meshheading:11920234-Adult,
pubmed-meshheading:11920234-Cytogenetic Analysis,
pubmed-meshheading:11920234-Female,
pubmed-meshheading:11920234-Fusion Proteins, bcr-abl,
pubmed-meshheading:11920234-Gene Rearrangement,
pubmed-meshheading:11920234-Humans,
pubmed-meshheading:11920234-In Situ Hybridization, Fluorescence,
pubmed-meshheading:11920234-Interphase,
pubmed-meshheading:11920234-Male,
pubmed-meshheading:11920234-Middle Aged,
pubmed-meshheading:11920234-Philadelphia Chromosome,
pubmed-meshheading:11920234-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:11920234-Prospective Studies,
pubmed-meshheading:11920234-Reproducibility of Results,
pubmed-meshheading:11920234-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:11920234-Sensitivity and Specificity,
pubmed-meshheading:11920234-Translocation, Genetic
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pubmed:year |
2001
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pubmed:articleTitle |
Detection of BCR/ABL rearrangements in adult acute lymphoblastic leukemia using a highly sensitive interphase fluorescence in situ hybridization method (D-FISH).
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pubmed:affiliation |
Department of Cellular Biotechnologies and Hematology, University 'La Sapienza', Rome, Italy. mancini@bce.med.uniromal.it
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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