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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2002-3-27
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pubmed:abstractText |
Earlier open-label clinical trials have provided conflicting data on the effects of cyclosporin-A (CsA) on the clinical course and immune status of patients with HIV disease. With the prospects for wider use of CsA in the setting of solid organ transplantation in HIV-infected persons, data on the safety and immunologic activity of this agent are needed. We report here the results of a randomized, double-blind, placebo-controlled trial to assess the safety and immunologic activity of CsA administration in early HIV disease.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1525-4135
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pubmed:author |
pubmed-author:AIDS Clinical Trials Group 334 Investigators,
pubmed-author:CalabreseLeonard HLH,
pubmed-author:CoombsRobert WRW,
pubmed-author:FoxLawrenceL,
pubmed-author:JohnsonRonaldR,
pubmed-author:LedermanMichael MMM,
pubmed-author:MildvanDonnaD,
pubmed-author:ParekhNamitaN,
pubmed-author:SchockBarbaraB,
pubmed-author:SpritzlerJohnJ,
pubmed-author:Yen-LiebermanBelindaB
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
356-62
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11917239-Adult,
pubmed-meshheading:11917239-CD4 Lymphocyte Count,
pubmed-meshheading:11917239-Cyclosporine,
pubmed-meshheading:11917239-Double-Blind Method,
pubmed-meshheading:11917239-Female,
pubmed-meshheading:11917239-HIV Infections,
pubmed-meshheading:11917239-HIV-1,
pubmed-meshheading:11917239-Humans,
pubmed-meshheading:11917239-Immunosuppressive Agents,
pubmed-meshheading:11917239-Male,
pubmed-meshheading:11917239-Organ Transplantation,
pubmed-meshheading:11917239-RNA, Viral,
pubmed-meshheading:11917239-Treatment Outcome
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pubmed:year |
2002
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pubmed:articleTitle |
Placebo-controlled trial of cyclosporin-A in HIV-1 disease: implications for solid organ transplantation.
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pubmed:affiliation |
Department of Rheumatic and Immunologic Diseases, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. calabrl@ccf.org
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Multicenter Study
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