Linked Life Data

1191186

Source:http://linkedlifedata.com/resource/pubmed/id/1191186

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1976-1-26
pubmed:abstractText
Human cells prelabeled with [32P]phosphate were exposed to UV and then pulse-labeled with [3H]thymidine. The DNA from these cells was subsequently treated with T4 endonuclease V, an enzyme which specifically nicks DNA at positions adjacent to pyrimidine dimers. Sedimentation in alkaline sucrose gradients revealed that both the DNA made before and that made after irradiation contained nuclease-sensitive sites, indicating that a recombinational process between these DNAs might be occurring during postirradiation incubation. Sedimentation in neutral sucros gradients showed that the molecular weight of native DNA remained unchanged for both DNAs upon endonuclease treatment, indicating that gaps opposite dimers are not necessarily formed after irradiation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0090-5542
pubmed:author
pubmed:issnType
Print
pubmed:volume
5B
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
639-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Postreplication repair in human cells: on the presence of gaps opposite dimers and recombination.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.