|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2002-3-22
|
|
pubmed:abstractText |
Mutations in the NOD2 gene are strongly associated with susceptibility to Crohn's disease (CD). We analyzed a large cohort of European patients with inflammatory bowel disease to determine which mutations confer susceptibility, the degree of risk conferred, their prevalence in familial and sporadic forms of the disease, and whether they are associated with site of disease.
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0016-5085
|
|
pubmed:author |
pubmed-author:CroucherPeter J PPJ,
pubmed-author:CuthbertAndrew PAP,
pubmed-author:FisherSheila ASA,
pubmed-author:ForbesAlastairA,
pubmed-author:HampeJochenJ,
pubmed-author:KingKathyK,
pubmed-author:LewisCathryn MCM,
pubmed-author:MansfieldJohnJ,
pubmed-author:MascherettiSilviaS,
pubmed-author:MathewChristopher GCG,
pubmed-author:MirzaMuddassar MMM,
pubmed-author:SandersonJeremyJ,
pubmed-author:SchreiberStefanS
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
122
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
867-74
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:11910337-Carrier Proteins,
pubmed-meshheading:11910337-Cohort Studies,
pubmed-meshheading:11910337-Colon,
pubmed-meshheading:11910337-Crohn Disease,
pubmed-meshheading:11910337-Family Health,
pubmed-meshheading:11910337-Female,
pubmed-meshheading:11910337-Frameshift Mutation,
pubmed-meshheading:11910337-Genetic Linkage,
pubmed-meshheading:11910337-Genetic Predisposition to Disease,
pubmed-meshheading:11910337-Humans,
pubmed-meshheading:11910337-Ileum,
pubmed-meshheading:11910337-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:11910337-Male,
pubmed-meshheading:11910337-Mutation, Missense,
pubmed-meshheading:11910337-Nod2 Signaling Adaptor Protein,
pubmed-meshheading:11910337-Phenotype,
pubmed-meshheading:11910337-Polymorphism, Single Nucleotide,
pubmed-meshheading:11910337-Proteins,
pubmed-meshheading:11910337-Risk Factors
|
|
pubmed:year |
2002
|
|
pubmed:articleTitle |
The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease.
|
|
pubmed:affiliation |
Division of Medical and Molecular Genetics, Guy's, King's, and St Thomas' School of Medicine, London, England, United Kingdom.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
