Linked Life Data

11910188

Source:http://linkedlifedata.com/resource/pubmed/id/11910188

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-6
pubmed:dateCreated
2002-3-22
pubmed:abstractText
Several procoagulant proteins from snake venoms have been isolated and characterized. They are either serine proteinases or metalloproteinases, which activate specific zymogens of coagulation factors and initiate the coagulation cascade. These procoagulant proteins are useful in treating various thrombotic and hemostatic conditions and contribute to our understanding of molecular details in the activation of specific coagulation factors. Recent studies have shown that the prothrombin activators with serine proteinase activity are structurally and functionally similar to mammalian coagulation factors. Their structural studies should provide us insight into prothrombinase complex formation. Here, we present an overview of snake venom procoagulant factors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0301-0147
pubmed:author
pubmed:copyrightInfo
Copyright 2002 S. Karger AG, Basel
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
218-24
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Procoagulant proteins from snake venoms.
pubmed:affiliation
Department of Biological Sciences, Faculty of Science, Block S2 Room 04-11, 14 Science Drive, National University of Singapore, Singapore 117543. dbskinim@nus.edu.sg
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't