Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2002-4-3
pubmed:abstractText
High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date, the vast majority of these experiments have focused on specific biological processes and perturbations. Here, we have generated and analyzed gene expression from a set of samples spanning a broad range of biological conditions. Specifically, we profiled gene expression from 91 human and mouse samples across a diverse array of tissues, organs, and cell lines. Because these samples predominantly come from the normal physiological state in the human and mouse, this dataset represents a preliminary, but substantial, description of the normal mammalian transcriptome. We have used this dataset to illustrate methods of mining these data, and to reveal insights into molecular and physiological gene function, mechanisms of transcriptional regulation, disease etiology, and comparative genomics. Finally, to allow the scientific community to use this resource, we have built a free and publicly accessible website (http://expression.gnf.org) that integrates data visualization and curation of current gene annotations.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-10485450, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-10698627, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-10854408, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-11005875, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-11015593, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-11036930, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-11062470, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-11068203, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-11073444, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-11118138, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-11148678, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-11158616, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-11181995, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-11226216, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-11237011, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-11507037, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-2231712, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-3880345, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-7497123, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-9092566, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-9223186, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-9415887, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-9634850, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-9843981, http://linkedlifedata.com/resource/pubmed/commentcorrection/11904358-9872452
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:day
2
pubmed:volume
99
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4465-70
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Large-scale analysis of the human and mouse transcriptomes.
pubmed:affiliation
Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't