Linked Life Data

11903376

Source:http://linkedlifedata.com/resource/pubmed/id/11903376

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-3-20
pubmed:abstractText
Radiation-induced cancer, a rare clinical entity, is often difficult to diagnose and manage. This study reports a series of five cases of radiocarcinogenesis of the pharynx and/or larynx that developed after external radiotherapy. The primary lesion was diagnosed at a mean age of 50 years (+/-12.9) and the radiation-induced cancer at a mean age of 59 years (+/-13.1), giving a latent period of 9 years (+/-3.7). Analysis of gammagraphic records indicated that four of the patients had developed a secondary tumour in the penumbra of irradiation fields. In these zones, the delivered dose was between 20 and 80% of the prescribed dose, corresponding to an estimated cumulative mean dose of 14.1-56.3 Gy. These results are compared with data in the literature to determine the diagnostic criteria for radiation-induced cancer, possible predisposition (genetic or acquired) and the dose effect.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0307-7772
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
68-74
pubmed:dateRevised
2005-5-2
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Radiation-induced cancers of the pharynx and larynx: a study of five clinical cases.
pubmed:affiliation
Service de clinique O.R.L. et de chirurgie cervico-faciale, CHU de Nantes, Hotel-Dieu, Place A. Ricordeau, BP 1005, 44093 Nantes Cedex 01, France. omalard@sante.univ-nantes.fr
pubmed:publicationType
Journal Article, Case Reports