Linked Life Data

1190315

Source:http://linkedlifedata.com/resource/pubmed/id/1190315

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1976-1-17
pubmed:abstractText
Renal transport was studied by direct analysis of specific segments of the nephron for the substance transported. Rats were given inulin plus loads of glutamate or aspartate. Glomeruli, six different identified segments, and patches from thin-limb and papillary areas were dissected from individual nephrons in freeze-dried sections. Large amounts of the amino acid (up to 35 mmol/kg) accumulated in segments in which transport is believed to occur. With subthreshold loads, large amino acid increments were confined to earlier proximal segments. With loads above threshold, increases occurred throughout the proximal tubule. The early convoluted tubule probably has less transport activity than the rest of the proximal tubule. Both dicarboxylic amino acids accumulate in large amount when one is given. Aspartate is probably formed within the tubule after a glutamate load. This new histochemical approach may have general applicability for more precise localization of transport cells, for assessing changes in those cells during transport, and for study of structures inaccessible to micropuncture.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
229
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1034-44
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
A quantitative histochemical approach to renal transport. I. Aspartate and glutamate.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.