Source:http://linkedlifedata.com/resource/pubmed/id/11901312
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2002-3-19
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pubmed:abstractText |
Dacarbazine (DTIC) is commonly used for the treatment of malignant melanoma and Hodgkin's disease. A very rare complication of this cytotoxic agent is acute vascular hepatic damage, e.g. veno-occlusive disease or Budd-Chiari syndrome. The pathophysiological mechanism involved seems to be an immune reaction. This complication is frequently fatal. We report a patient who developed severe hepatic failure following DTIC treatment who responded favorably to treatment with glucocorticosteroid.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0959-4973
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
177-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11901312-Aged,
pubmed-meshheading:11901312-Antineoplastic Agents, Alkylating,
pubmed-meshheading:11901312-Dacarbazine,
pubmed-meshheading:11901312-Eye Neoplasms,
pubmed-meshheading:11901312-Glucocorticoids,
pubmed-meshheading:11901312-Humans,
pubmed-meshheading:11901312-Liver Failure,
pubmed-meshheading:11901312-Male,
pubmed-meshheading:11901312-Melanoma,
pubmed-meshheading:11901312-Treatment Outcome
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pubmed:year |
2002
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pubmed:articleTitle |
The role of glucocorticoids in the treatment of fulminant hepatitis induced by dacarbazine.
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pubmed:affiliation |
Department of Medicine A and Liver Clinic-Meir Hospital, Kfar-Saba and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
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pubmed:publicationType |
Journal Article,
Case Reports
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