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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2002-3-15
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pubmed:abstractText |
To determine dose-limiting toxicity (DLT) and maximum-tolerated dose (MTD) of a protracted, intermittent schedule of daily 30-minute infusions of topotecan (TPT) for up to 12 consecutive days, every 3 weeks, in children with refractory leukemia.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0732-183X
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pubmed:author |
pubmed-author:BaruchelSylvainS,
pubmed-author:BectonDavid LeeDL,
pubmed-author:BernsteinMark LML,
pubmed-author:FurmanWayne LWL,
pubmed-author:KepnerJames LJL,
pubmed-author:KirsteinMarkM,
pubmed-author:KungFaithF,
pubmed-author:PrattCharlesC,
pubmed-author:SteuberC PhilipCP,
pubmed-author:StewartClinton FCF,
pubmed-author:ViettiTeresa JTJ
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1617-24
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11896112-Adolescent,
pubmed-meshheading:11896112-Adult,
pubmed-meshheading:11896112-Antineoplastic Agents,
pubmed-meshheading:11896112-Child,
pubmed-meshheading:11896112-Child, Preschool,
pubmed-meshheading:11896112-Drug Administration Schedule,
pubmed-meshheading:11896112-Female,
pubmed-meshheading:11896112-Humans,
pubmed-meshheading:11896112-Infant,
pubmed-meshheading:11896112-Infusions, Intravenous,
pubmed-meshheading:11896112-Leukemia, Myeloid, Acute,
pubmed-meshheading:11896112-Male,
pubmed-meshheading:11896112-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:11896112-Topotecan,
pubmed-meshheading:11896112-Treatment Outcome
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pubmed:year |
2002
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pubmed:articleTitle |
Protracted intermittent schedule of topotecan in children with refractory acute leukemia: a pediatric oncology group study.
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pubmed:affiliation |
Department of Hematology-Oncology, St Jude Children's Research Hospital, Memphis, TN, USA. wayne.furman@stjude.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Clinical Trial, Phase I
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