| pubmed-article:11895290 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11895290 | lifeskim:mentions | umls-concept:C0031809 | lld:lifeskim |
| pubmed-article:11895290 | lifeskim:mentions | umls-concept:C0266929 | lld:lifeskim |
| pubmed-article:11895290 | lifeskim:mentions | umls-concept:C0021755 | lld:lifeskim |
| pubmed-article:11895290 | lifeskim:mentions | umls-concept:C0039593 | lld:lifeskim |
| pubmed-article:11895290 | lifeskim:mentions | umls-concept:C0314657 | lld:lifeskim |
| pubmed-article:11895290 | lifeskim:mentions | umls-concept:C0205082 | lld:lifeskim |
| pubmed-article:11895290 | lifeskim:mentions | umls-concept:C1285573 | lld:lifeskim |
| pubmed-article:11895290 | lifeskim:mentions | umls-concept:C1511545 | lld:lifeskim |
| pubmed-article:11895290 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:11895290 | pubmed:dateCreated | 2002-3-15 | lld:pubmed |
| pubmed-article:11895290 | pubmed:abstractText | This review addresses the ability of a commercially available genetic susceptibility test to determine the risk of developing severe chronic periodontitis. The test is used to detect the simultaneous occurrence of allele 2 at the IL-1A+4845 and IL-1B+3954 loci. If both of these polymorphisms are present, patients are referred to as being genotype-positive and considered predisposed to becoming afflicted with severe chronic periodontitis. A basic premise of this test is the assumption that individuals who are genotype-positive produce increased amounts of IL-beta in response to microbial lipopolysaccharides, which allegedly predisposes them to an exaggerated inflammatory response and an increased incidence of chronic periodontitis. | lld:pubmed |
| pubmed-article:11895290 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11895290 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11895290 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11895290 | pubmed:citationSubset | D | lld:pubmed |
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| pubmed-article:11895290 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11895290 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:11895290 | pubmed:issn | 0022-3492 | lld:pubmed |
| pubmed-article:11895290 | pubmed:author | pubmed-author:HartThomas... | lld:pubmed |
| pubmed-article:11895290 | pubmed:author | pubmed-author:GreensteinGar... | lld:pubmed |
| pubmed-article:11895290 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11895290 | pubmed:volume | 73 | lld:pubmed |
| pubmed-article:11895290 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11895290 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11895290 | pubmed:pagination | 231-47 | lld:pubmed |
| pubmed-article:11895290 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:11895290 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:11895290 | pubmed:articleTitle | A critical assessment of interleukin-1 (IL-1) genotyping when used in a genetic susceptibility test for severe chronic periodontitis. | lld:pubmed |
| pubmed-article:11895290 | pubmed:affiliation | University of Medicine and Dentistry of New Jersey, Newark, USA. Hgreens123@aol.com | lld:pubmed |
| pubmed-article:11895290 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11895290 | pubmed:publicationType | Meta-Analysis | lld:pubmed |
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