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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2002-3-14
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pubmed:abstractText |
Reactive oxygen intermediates play an important role in the inflammatory processes of rheumatoid arthritis. Cyclooxygenase-2 is an inducible form of an enzyme involved in prostanoid biosynthesis. This study linked peroxynitrite (ONOO-) to the signaling pathways that induce COX-2.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0392-856X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
59-62
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:11892711-Arthritis, Rheumatoid,
pubmed-meshheading:11892711-Cells, Cultured,
pubmed-meshheading:11892711-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:11892711-Humans,
pubmed-meshheading:11892711-Molsidomine,
pubmed-meshheading:11892711-Nitric Oxide,
pubmed-meshheading:11892711-Nitric Oxide Donors,
pubmed-meshheading:11892711-Peroxynitrous Acid,
pubmed-meshheading:11892711-Prostaglandin-Endoperoxide Synthases,
pubmed-meshheading:11892711-RNA, Messenger,
pubmed-meshheading:11892711-Synovial Membrane
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pubmed:articleTitle |
The role of peroxynitrite in cyclooxygenase-2 expression of rheumatoid synovium.
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pubmed:affiliation |
First Department of Internal Medicine, Nagasaki University School of Medicine, Japan. migita@net.nagasaki-u.ac.jp
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pubmed:publicationType |
Journal Article
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