| pubmed-article:11891147 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11891147 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:11891147 | lifeskim:mentions | umls-concept:C0225385 | lld:lifeskim |
| pubmed-article:11891147 | lifeskim:mentions | umls-concept:C0025568 | lld:lifeskim |
| pubmed-article:11891147 | lifeskim:mentions | umls-concept:C0042839 | lld:lifeskim |
| pubmed-article:11891147 | lifeskim:mentions | umls-concept:C0004048 | lld:lifeskim |
| pubmed-article:11891147 | lifeskim:mentions | umls-concept:C0334044 | lld:lifeskim |
| pubmed-article:11891147 | lifeskim:mentions | umls-concept:C0031928 | lld:lifeskim |
| pubmed-article:11891147 | lifeskim:mentions | umls-concept:C0023981 | lld:lifeskim |
| pubmed-article:11891147 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:11891147 | pubmed:dateCreated | 2002-3-13 | lld:pubmed |
| pubmed-article:11891147 | pubmed:abstractText | The objective of this preliminary uncontrolled study was twofold: First, to assess the feasibility of retinyl palmitate inhalation and second, to analyze the changes of metaplastic lesions of the respiratory epithelium (metaplasia or dysplasia) following retinyl palmitate inhalation. The response to a daily dose of 18.000 I.U. retinyl palmitate by inhalation over a period of 3 month was assessed in 11 subjects (9 smokers, 2 ex-smokers). Using white-light bronchoscopy combined with autofluorescence bronchoscopy, bronchial biopsies were taken before and after a 3 month-period. The biopsy samples were evaluated blind by a referee lung pathologist. The overall response rate (remission or partial remission) was 56% (95% CI 0.30 0.79; p<0.05). These data suggest that inhalation of retinyl esters could be a promising therapeutical approach for chemoprevention of lung cancer. Vitamin A; chemoprevention; lung cancer; squamous metaplasia; dysplasia; retinoids | lld:pubmed |
| pubmed-article:11891147 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11891147 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11891147 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11891147 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11891147 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11891147 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11891147 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11891147 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:11891147 | pubmed:issn | 0949-2321 | lld:pubmed |
| pubmed-article:11891147 | pubmed:author | pubmed-author:HäussingerKK | lld:pubmed |
| pubmed-article:11891147 | pubmed:author | pubmed-author:TritschlerJJ | lld:pubmed |
| pubmed-article:11891147 | pubmed:author | pubmed-author:MarkusAA | lld:pubmed |
| pubmed-article:11891147 | pubmed:author | pubmed-author:BiesalskiH... | lld:pubmed |
| pubmed-article:11891147 | pubmed:author | pubmed-author:ScheuchGG | lld:pubmed |
| pubmed-article:11891147 | pubmed:author | pubmed-author:MühlhöferAA | lld:pubmed |
| pubmed-article:11891147 | pubmed:author | pubmed-author:GollyII | lld:pubmed |
| pubmed-article:11891147 | pubmed:author | pubmed-author:JanyB HBH | lld:pubmed |
| pubmed-article:11891147 | pubmed:author | pubmed-author:KohlhäuflMM | lld:pubmed |
| pubmed-article:11891147 | pubmed:author | pubmed-author:Morresi-HaufA... | lld:pubmed |
| pubmed-article:11891147 | pubmed:author | pubmed-author:StanzelFF | lld:pubmed |
| pubmed-article:11891147 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11891147 | pubmed:day | 21 | lld:pubmed |
| pubmed-article:11891147 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:11891147 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11891147 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11891147 | pubmed:pagination | 72-8 | lld:pubmed |
| pubmed-article:11891147 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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| pubmed-article:11891147 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:11891147 | pubmed:articleTitle | Inhalation of aerosolized vitamin a: reversibility of metaplasia and dysplasia of human respiratory epithelia -- a prospective pilot study. | lld:pubmed |
| pubmed-article:11891147 | pubmed:affiliation | Asklepios Center for Respiratory Medicine and Thoracic Surgery, Munich-Gauting, Germany. | lld:pubmed |
| pubmed-article:11891147 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11891147 | pubmed:publicationType | Clinical Trial | lld:pubmed |
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