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11889464
Source:
http://linkedlifedata.com/resource/pubmed/id/11889464
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Statements in which the resource exists as a subject.
Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0010453
,
umls-concept:C0086418
,
umls-concept:C0348014
,
umls-concept:C0442805
,
umls-concept:C1517499
,
umls-concept:C1547538
,
umls-concept:C1549542
pubmed:dateCreated
2002-3-12
pubmed:abstractText
To investigate the regulation of expression and the role of the RhoA gene in the human trabecular meshwork (TM). To attempt to modulate outflow facility by gene transfer of the RhoA gene's dominant-negative mutant protein.
pubmed:grant
http://linkedlifedata.com/resource/pubmed/grant/EY01894
,
http://linkedlifedata.com/resource/pubmed/grant/EY11906
,
http://linkedlifedata.com/resource/pubmed/grant/EY12172
,
http://linkedlifedata.com/resource/pubmed/grant/EY13126
,
http://linkedlifedata.com/resource/pubmed/grant/P30EY05722
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9605351
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Actins
,
http://linkedlifedata.com/resource/pubmed/chemical/Cytoskeletal Proteins
,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins
,
http://linkedlifedata.com/resource/pubmed/chemical/PXN protein, human
,
http://linkedlifedata.com/resource/pubmed/chemical/Paxillin
,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphoproteins
,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
,
http://linkedlifedata.com/resource/pubmed/chemical/rhoA GTP-Binding Protein
,
http://linkedlifedata.com/resource/pubmed/chemical/zonula occludens-1 protein
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1090-0535
pubmed:author
pubmed-author:BorrásTeresaT
,
pubmed-author:EpsteinDavid LDL
,
pubmed-author:GargRahulR
,
pubmed-author:O'BrienEdward TET
,
pubmed-author:RowletteLaura-Leigh SLL
,
pubmed-author:VittitowJason LJL
pubmed:issnType
Electronic
pubmed:day
6
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
32-44
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:11889464-Actins
,
pubmed-meshheading:11889464-Adenoviridae
,
pubmed-meshheading:11889464-Aged
,
pubmed-meshheading:11889464-Aged, 80 and over
,
pubmed-meshheading:11889464-Aqueous Humor
,
pubmed-meshheading:11889464-Blotting, Northern
,
pubmed-meshheading:11889464-Cytoskeletal Proteins
,
pubmed-meshheading:11889464-Cytoskeleton
,
pubmed-meshheading:11889464-Female
,
pubmed-meshheading:11889464-Gene Expression Regulation
,
pubmed-meshheading:11889464-Gene Transfer Techniques
,
pubmed-meshheading:11889464-Genetic Vectors
,
pubmed-meshheading:11889464-Humans
,
pubmed-meshheading:11889464-Male
,
pubmed-meshheading:11889464-Membrane Proteins
,
pubmed-meshheading:11889464-Organ Culture Techniques
,
pubmed-meshheading:11889464-Paxillin
,
pubmed-meshheading:11889464-Perfusion
,
pubmed-meshheading:11889464-Phosphoproteins
,
pubmed-meshheading:11889464-Pressure
,
pubmed-meshheading:11889464-RNA, Messenger
,
pubmed-meshheading:11889464-Trabecular Meshwork
,
pubmed-meshheading:11889464-rhoA GTP-Binding Protein
pubmed:year
2002
pubmed:articleTitle
Gene transfer of dominant-negative RhoA increases outflow facility in perfused human anterior segment cultures.
pubmed:affiliation
Dept. of Ophthalmology, Duke University Medical Center, Durham, NC 27710, USA. jason.vittitow@duke.edu
pubmed:publicationType
Journal Article
,
Research Support, U.S. Gov't, P.H.S.
,
Research Support, Non-U.S. Gov't