rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2002-3-12
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pubmed:abstractText |
Peroxisome proliferator-activated receptors (PPARs) are transcription factors of the nuclear receptor superfamily. It has been reported that the thiazolidinediones, which are antidiabetic agents and high-affinity ligands for PPARgamma, regulate growth of vascular cells. In the present study, we examined the role of PPARgamma in angiotensin II (Ang II)-induced hypertrophy of neonatal rat cardiac myocytes and in pressure overload-induced cardiac hypertrophy of mice.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Actins,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II,
http://linkedlifedata.com/resource/pubmed/chemical/Atrial Natriuretic Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Chromans,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoglycemic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cytoplasmic and Nuclear,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazolidinediones,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/pioglitazone,
http://linkedlifedata.com/resource/pubmed/chemical/rosiglitazone,
http://linkedlifedata.com/resource/pubmed/chemical/troglitazone
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
12
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pubmed:volume |
105
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1240-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11889020-Actins,
pubmed-meshheading:11889020-Angiotensin II,
pubmed-meshheading:11889020-Animals,
pubmed-meshheading:11889020-Atrial Natriuretic Factor,
pubmed-meshheading:11889020-Body Weight,
pubmed-meshheading:11889020-Cardiomegaly,
pubmed-meshheading:11889020-Cell Size,
pubmed-meshheading:11889020-Cells, Cultured,
pubmed-meshheading:11889020-Chromans,
pubmed-meshheading:11889020-Disease Models, Animal,
pubmed-meshheading:11889020-Gene Expression,
pubmed-meshheading:11889020-Heart,
pubmed-meshheading:11889020-Heterozygote,
pubmed-meshheading:11889020-Hypoglycemic Agents,
pubmed-meshheading:11889020-Ligands,
pubmed-meshheading:11889020-Mice,
pubmed-meshheading:11889020-Mice, Knockout,
pubmed-meshheading:11889020-Myocardium,
pubmed-meshheading:11889020-Organ Size,
pubmed-meshheading:11889020-Rats,
pubmed-meshheading:11889020-Rats, Wistar,
pubmed-meshheading:11889020-Receptors, Cytoplasmic and Nuclear,
pubmed-meshheading:11889020-Thiazoles,
pubmed-meshheading:11889020-Thiazolidinediones,
pubmed-meshheading:11889020-Transcription Factors
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pubmed:year |
2002
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pubmed:articleTitle |
Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo.
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pubmed:affiliation |
Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
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pubmed:publicationType |
Journal Article
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