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rdf:type |
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lifeskim:mentions |
umls-concept:C0005847,
umls-concept:C0014257,
umls-concept:C0017887,
umls-concept:C0018338,
umls-concept:C0037083,
umls-concept:C0086418,
umls-concept:C0205245,
umls-concept:C0205474,
umls-concept:C0542341,
umls-concept:C0936012,
umls-concept:C1550147,
umls-concept:C1710082
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pubmed:issue |
10
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pubmed:dateCreated |
2002-3-12
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pubmed:abstractText |
In experimental animal models, long-term in vivo treatment with nitroglycerin (NTG) induces both endothelial dysfunction and tolerance to nitrates. However, it is still controversial whether nitrate tolerance in humans is associated with both endothelial dysfunction and impaired vascular response to nitrovasodilator-derived NO.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cell Adhesion Molecules,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic GMP,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic GMP-Dependent Protein Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Guanylate Cyclase,
http://linkedlifedata.com/resource/pubmed/chemical/Microfilament Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Nitroglycerin,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cytoplasmic and Nuclear,
http://linkedlifedata.com/resource/pubmed/chemical/Vasodilator Agents,
http://linkedlifedata.com/resource/pubmed/chemical/cGMP-dependent protein kinase Ialpha,
http://linkedlifedata.com/resource/pubmed/chemical/soluble guanylyl cyclase,
http://linkedlifedata.com/resource/pubmed/chemical/vasodilator-stimulated...
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:MünzelThomasT,
pubmed-author:MeinertzThomasT,
pubmed-author:OelzeMathiasM,
pubmed-author:ReichenspurnerHermannH,
pubmed-author:ReiterBeateB,
pubmed-author:RinzeRuthR,
pubmed-author:SchulzEberhardE,
pubmed-author:TsilimingasNikolausN,
pubmed-author:WalterUlrichU,
pubmed-author:WendtMariaM,
pubmed-author:Woelken-WeckmüllerSilkeS
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pubmed:issnType |
Electronic
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pubmed:day |
12
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pubmed:volume |
105
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1170-5
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11889009-Aged,
pubmed-meshheading:11889009-Blood Vessels,
pubmed-meshheading:11889009-Cell Adhesion Molecules,
pubmed-meshheading:11889009-Coronary Artery Bypass,
pubmed-meshheading:11889009-Coronary Disease,
pubmed-meshheading:11889009-Cyclic GMP,
pubmed-meshheading:11889009-Cyclic GMP-Dependent Protein Kinases,
pubmed-meshheading:11889009-Dose-Response Relationship, Drug,
pubmed-meshheading:11889009-Drug Tolerance,
pubmed-meshheading:11889009-Endothelium, Vascular,
pubmed-meshheading:11889009-Female,
pubmed-meshheading:11889009-Guanylate Cyclase,
pubmed-meshheading:11889009-Humans,
pubmed-meshheading:11889009-Immunohistochemistry,
pubmed-meshheading:11889009-Male,
pubmed-meshheading:11889009-Mammary Arteries,
pubmed-meshheading:11889009-Microfilament Proteins,
pubmed-meshheading:11889009-Middle Aged,
pubmed-meshheading:11889009-Nitric Oxide,
pubmed-meshheading:11889009-Nitroglycerin,
pubmed-meshheading:11889009-Phosphoproteins,
pubmed-meshheading:11889009-Phosphorylation,
pubmed-meshheading:11889009-Radial Artery,
pubmed-meshheading:11889009-Receptors, Cytoplasmic and Nuclear,
pubmed-meshheading:11889009-Saphenous Vein,
pubmed-meshheading:11889009-Signal Transduction,
pubmed-meshheading:11889009-Vasodilation,
pubmed-meshheading:11889009-Vasodilator Agents
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pubmed:year |
2002
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pubmed:articleTitle |
Functional and biochemical analysis of endothelial (dys)function and NO/cGMP signaling in human blood vessels with and without nitroglycerin pretreatment.
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pubmed:affiliation |
University Hospital Eppendorf, Division of Cardiology, Hamburg, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
In Vitro,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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