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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9308
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pubmed:dateCreated |
2002-3-12
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pubmed:abstractText |
The use of abacavir--a potent HIV-1 nucleoside-analogue reverse-transcriptase inhibitor--is complicated by a potentially life-threatening hypersensitivity syndrome in about 5% of cases. Genetic factors influencing the immune response to abacavir might confer susceptibility. We aimed to find associations between MHC alleles and abacavir hypersensitivity in HIV-1-positive individuals treated with abacavir.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0140-6736
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pubmed:author |
pubmed-author:CastleyAA,
pubmed-author:ChristiansenF TFT,
pubmed-author:JamesII,
pubmed-author:MallalSS,
pubmed-author:MamotteCC,
pubmed-author:MartinA MAM,
pubmed-author:MaserMM,
pubmed-author:MaxwellDD,
pubmed-author:MooreCC,
pubmed-author:NolanDD,
pubmed-author:SayerDD,
pubmed-author:WittCC
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pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
359
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
727-32
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:11888582-Adult,
pubmed-meshheading:11888582-Alleles,
pubmed-meshheading:11888582-Anti-HIV Agents,
pubmed-meshheading:11888582-Cohort Studies,
pubmed-meshheading:11888582-Dideoxynucleosides,
pubmed-meshheading:11888582-Drug Hypersensitivity,
pubmed-meshheading:11888582-Female,
pubmed-meshheading:11888582-Gene Frequency,
pubmed-meshheading:11888582-Genetic Markers,
pubmed-meshheading:11888582-HIV Infections,
pubmed-meshheading:11888582-HIV-1,
pubmed-meshheading:11888582-HLA-B Antigens,
pubmed-meshheading:11888582-HLA-DQ Antigens,
pubmed-meshheading:11888582-HLA-DR7 Antigen,
pubmed-meshheading:11888582-Haplotypes,
pubmed-meshheading:11888582-Humans,
pubmed-meshheading:11888582-Male,
pubmed-meshheading:11888582-Middle Aged,
pubmed-meshheading:11888582-Reverse Transcriptase Inhibitors
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pubmed:year |
2002
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pubmed:articleTitle |
Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir.
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pubmed:affiliation |
Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital and Murdoch University, Western Australia, Perth, Australia. mallal@prodigal.murdoch.edu.au
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pubmed:publicationType |
Journal Article
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