Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-3-12
pubmed:abstractText
The aim of this in vitro study was to evaluate the effects of irradiation and fluoridation on the demineralization and remineralization patterns of root dentin. From the cervical regions of 84 bovine incisors, each of four dentinal blocks were prepared and randomly assigned to four groups: 1) no irradiation; 2) irradiation of specimens up to 60 Gy (2 Gy/d, 5 d/w); 3) no irradiation, but fluoridation of specimens for 5 min/d with Elmex Gelée; and 4) irradiation and daily fluoridation of specimens for 5 min/d. Subsequently, the specimens were demineralized for 2, 4, 6 or 8 days with acidulated hydroxyethylcellulose (n = 21), and Knoop hardness numbers (KHN) were determined before, as well as after the demineralization period. Then seven specimens from each group were fluoridated with one of three fluoride gels (Elmex Gelée [1.25%], STOP [0.4%], Fluoridgel [1.25%]; 2 x 15 min/d, 10 d), and immersed in synthetic saliva at a temperature of 37 degrees C. Finally, KHN for all specimens were determined. Irradiation resulted in a significant decrease in microhardness. There was a reduction in microhardness with increasing demineralization time in all groups. The highest percentage decrease in microhardness could be observed with group 1. Due to the preceding decrease of KHN in the irradiated specimens (group 2), these samples showed less percentage reduction in microhardness during demineralization when compared to group 1 (ANOVA; p < 0.001). The decrease in microhardness was significantly hampered by fluoridation in the non-irradiated, as well as in the irradiated samples (groups 3 and 4; p < 0.001). The remineralization with Fluoridgel resulted in the greatest increase in microhardness. It is concluded that demineralization can be hampered by regular fluoride application in irradiated dentin. However, due to the considerable irradiation effect, this benefit might be negligible.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0895-8831
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
104-10
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:11887512-Amines, pubmed-meshheading:11887512-Analysis of Variance, pubmed-meshheading:11887512-Animals, pubmed-meshheading:11887512-Cariostatic Agents, pubmed-meshheading:11887512-Cattle, pubmed-meshheading:11887512-Cellulose, pubmed-meshheading:11887512-Dentin, pubmed-meshheading:11887512-Diamines, pubmed-meshheading:11887512-Fluorides, pubmed-meshheading:11887512-Gels, pubmed-meshheading:11887512-Hardness, pubmed-meshheading:11887512-Lactic Acid, pubmed-meshheading:11887512-Radiation Dosage, pubmed-meshheading:11887512-Random Allocation, pubmed-meshheading:11887512-Sodium Fluoride, pubmed-meshheading:11887512-Statistics, Nonparametric, pubmed-meshheading:11887512-Tin Fluorides, pubmed-meshheading:11887512-Tooth Demineralization, pubmed-meshheading:11887512-Tooth Remineralization, pubmed-meshheading:11887512-Tooth Root
pubmed:year
2002
pubmed:articleTitle
Effect of demineralization and remineralization on microhardness of irradiated dentin.
pubmed:affiliation
Department of Operative Dentistry and Periodontology, School of Dental Medicine, University Hospital Benjamin Franklin, Freie Universität Berlin, Berlin, Germany. Kielbassa@medizin.fu-berlin.de
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't