Source:http://linkedlifedata.com/resource/pubmed/id/11886574
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2002-3-11
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pubmed:abstractText |
Neonatal alloimmune thrombocytopenia (NAIT) can occur when a mother is immunized against fetal platelet antigens inherited from the father. Early diagnosis and appropriate platelet transfusion therapy are essential to prevent life-threatening intracranial hemorrhage in the thrombocytopenic fetus or neonate. Five major human platelet antigen (HPA) systems are capable of causing this disorder with HPA-1a indicated most frequently. This article reviews the pathophysiology, clinical aspects, and management of NAIT. We also present our experience with treatment of neonates affected with this disorder.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1091-6660
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
32-5
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pubmed:dateRevised |
2006-8-26
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pubmed:meshHeading |
pubmed-meshheading:11886574-Antigens, Human Platelet,
pubmed-meshheading:11886574-Blood Group Incompatibility,
pubmed-meshheading:11886574-Epitopes,
pubmed-meshheading:11886574-Female,
pubmed-meshheading:11886574-Humans,
pubmed-meshheading:11886574-Infant, Newborn,
pubmed-meshheading:11886574-Platelet Transfusion,
pubmed-meshheading:11886574-Pregnancy,
pubmed-meshheading:11886574-Thrombocytopenia
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pubmed:year |
2002
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pubmed:articleTitle |
Neonatal alloimmune thrombocytopenia.
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pubmed:affiliation |
Department of Pathology, Indiana University Hospital, Indianapolis, Indiana 46202, USA.
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pubmed:publicationType |
Journal Article,
Review
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