Linked Life Data

11885747

Source:http://linkedlifedata.com/resource/pubmed/id/11885747

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2002-3-11
pubmed:abstractText
The endozepine-like peptide (ELP) is a testis-specific isoform of the acyl-CoA binding protein (ACBP) and shares the latter's peptide motif for binding mid-long chain acyl-CoA groups. ELP is expressed both as mRNA and protein at high levels in the testes of a wide range of mammals, including rodents, carnivores and ruminants. However, the ELP gene is progressively inactivated through primate evolution, with no protein detectable in a range of primates studied, including human. In nonprimate species, ELP is expressed in very late postmeiotic germ cell stages only, such that its function in these species is probably associated with the metabolism of the mature spermatozoon. Current research is looking at both the function of the ELP protein and the haploid regulation of the gene.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0936-6768
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
278-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
The evolution of the endozepine-like peptide (ELP) in the mammalian testis.
pubmed:affiliation
Institute for Hormone and Fertility Research, University of Hamburg, Germany. ivell@ihf.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Corrected and Republished Article