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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2002-3-8
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pubmed:abstractText |
The purpose of the present study is to examine the selectivity of various inhibitors towards the rat organic anion transporting polypeptides 1 (Oatp1: gene symbol Slc21a1) and 2 (Oatp2: Slc21a5). Methods: The inhibitory effects of 20 compounds on the Oatpl-mediated transport of estradiol 17beta-D-glucuronide and on the Oatp2-mediated transport of digoxin were examined in cDNA-transfected LLC-PK1cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Inflammatory Agents...,
http://linkedlifedata.com/resource/pubmed/chemical/Antibiotics, Antitubercular,
http://linkedlifedata.com/resource/pubmed/chemical/Antimalarials,
http://linkedlifedata.com/resource/pubmed/chemical/Digoxin,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Estradiol,
http://linkedlifedata.com/resource/pubmed/chemical/Ibuprofen,
http://linkedlifedata.com/resource/pubmed/chemical/Organic Anion Transporters,
http://linkedlifedata.com/resource/pubmed/chemical/Organic Anion Transporters...,
http://linkedlifedata.com/resource/pubmed/chemical/Organic Cation Transport Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Quinidine,
http://linkedlifedata.com/resource/pubmed/chemical/Quinine,
http://linkedlifedata.com/resource/pubmed/chemical/Rifampin,
http://linkedlifedata.com/resource/pubmed/chemical/Slc21a1 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Slco1a4 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Slco1c1 protein, rat
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0724-8741
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
147-53
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11883641-Algorithms,
pubmed-meshheading:11883641-Animals,
pubmed-meshheading:11883641-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:11883641-Antibiotics, Antitubercular,
pubmed-meshheading:11883641-Antimalarials,
pubmed-meshheading:11883641-Biological Transport, Active,
pubmed-meshheading:11883641-Digoxin,
pubmed-meshheading:11883641-Enzyme Inhibitors,
pubmed-meshheading:11883641-Estradiol,
pubmed-meshheading:11883641-Ibuprofen,
pubmed-meshheading:11883641-LLC-PK1 Cells,
pubmed-meshheading:11883641-Organic Anion Transporters,
pubmed-meshheading:11883641-Organic Anion Transporters, Sodium-Independent,
pubmed-meshheading:11883641-Organic Cation Transport Proteins,
pubmed-meshheading:11883641-Quinidine,
pubmed-meshheading:11883641-Quinine,
pubmed-meshheading:11883641-Rats,
pubmed-meshheading:11883641-Rifampin,
pubmed-meshheading:11883641-Swine
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pubmed:year |
2002
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pubmed:articleTitle |
Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport.
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pubmed:affiliation |
School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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