rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
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pubmed:dateCreated |
2002-3-8
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pubmed:abstractText |
Reported herein are two benign ossifying fibromyxoid tumors (OFMTs) of the soft tissues in axilla and terminal phalanx respectively. Both cases on immunohistochemistry (IHC) showed reactivity for vimentin, S-100 protein and glial fibrillary acidic protein (GFAP) antibodies. In addition, a focal/diffuse strong positivity for neurofilament (NF) and neuron specific enolase (NSE) was observed. Electron microscopy in one instance revealed abundant intermediate filaments, primitive cell junctions and a focally present external lamina. In the light of nerve cell differentiation of these tumors and the similarity of IHC profile and EM features of OFMT to a poorly differentiated malignant peripheral nerve sheath tumor (MPNST); it is suggested that OFMT is a variably differentiated PNST rather than a simple Schwannian neoplasm as is believed.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0377-4929
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
44
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
163-7
|
pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:11883138-Adult,
pubmed-meshheading:11883138-Glial Fibrillary Acidic Protein,
pubmed-meshheading:11883138-Humans,
pubmed-meshheading:11883138-Male,
pubmed-meshheading:11883138-Middle Aged,
pubmed-meshheading:11883138-Nerve Sheath Neoplasms,
pubmed-meshheading:11883138-Ossification, Heterotopic,
pubmed-meshheading:11883138-Phosphopyruvate Hydratase,
pubmed-meshheading:11883138-S100 Proteins,
pubmed-meshheading:11883138-Soft Tissue Neoplasms,
pubmed-meshheading:11883138-Tumor Markers, Biological,
pubmed-meshheading:11883138-Vimentin
|
pubmed:year |
2001
|
pubmed:articleTitle |
Nerve cell markers in ossifying fibromyxoid tumour of soft parts.
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pubmed:affiliation |
Department of Pathology, BYL Nair Ch Hospital, Mumbai.
|
pubmed:publicationType |
Journal Article,
Case Reports
|