Linked Life Data

11878232

Source:http://linkedlifedata.com/resource/pubmed/id/11878232

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2002-3-6
pubmed:abstractText
5 weeks development of streptozoticin-induced diabetes mellitus in the rats is accompanied with the increase of gastrin-releasing peptide (GRP) immunopositive neurons amount in parvocellular neurosecretory subdivisions of immunopositive fibers increased in these structures:the content of GRP increased in median eminence as well. In supraoptic nucleus and posterior magnocellular subdivision of paraventricular nucleus the amount of GRP-immunopositive neurons increased by the second week of diabetes development with its decrease by the fifth week. Thus, the increase of GRP synthesis in hypothalamic neurosecretory structures in diabetes mellitus may be considered as a compensatory reaction directed on the activation of the central mechanisms of feeding restriction and stimulation of insulin synthesis in the pancreas.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1026-3543
pubmed:author
pubmed:issnType
Print
pubmed:volume
120
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
46-51
pubmed:dateRevised
2011-5-9
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
[Morphofunctional characteristics of gastrin-releasing peptide synthesizing system of the hypothalamus in normal conditions and in experimental diabetes in rats].
pubmed:affiliation
Department of Pathophysiology, Medical University of Zaporozhye.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract