Linked Life Data

1187721

Source:http://linkedlifedata.com/resource/pubmed/id/1187721

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1976-1-16
pubmed:abstractText
Two weeks after parasagittal hypothalamic knife cuts, baseline eating was elevated and 300 mg/kg 2 deoxy-D-glucose (2DG) did not further stimulate food intake. Five weeks postoperatively the food intake baseline had fallen and an eating response to 300 mg/kg 2DG was now seen (p less than 0.005). In this delayed (static) phase intake was also stimulated by 150 mg/kg 2DG (p less than 0.005). 600 mg/kg did not stimulate intake in the lesioned rats at any time, although sham-operated rats always responded positively to this high dose. In conclusion, the neural substrate damaged in hypothalamic hyperphagic rats does not appear to mediate eating in response to glucopribation. The eating response is masked by high baseline intake in the dynamic phase, but reappears in the static phase.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
583-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Glucoprivic (2DG) eating in rats despite knife cut induced hyperphagia.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.