Source:http://linkedlifedata.com/resource/pubmed/id/11874410
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2002-3-4
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pubmed:abstractText |
Hypercortisolism is associated with impaired glucose tolerance and insulin resistance. For many years hydrocortisone 30 mg was the standard total daily replacement dose in adult hypopituitarism. The use of this conventional dose has now been shown to result in mild biochemical hypercortisolism and might contribute to the increased cardiovascular risk reported in hypopituitarism. The use of lower doses of hydrocortisone replacement therapy might prevent some of the adverse metabolic effects seen with conventional doses.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0300-0664
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-201
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:11874410-Administration, Oral,
pubmed-meshheading:11874410-Adult,
pubmed-meshheading:11874410-Blood Glucose,
pubmed-meshheading:11874410-Cross-Over Studies,
pubmed-meshheading:11874410-Drug Administration Schedule,
pubmed-meshheading:11874410-Female,
pubmed-meshheading:11874410-Glucose Clamp Technique,
pubmed-meshheading:11874410-Humans,
pubmed-meshheading:11874410-Hydrocortisone,
pubmed-meshheading:11874410-Hypopituitarism,
pubmed-meshheading:11874410-Infusions, Intravenous,
pubmed-meshheading:11874410-Insulin,
pubmed-meshheading:11874410-Liver,
pubmed-meshheading:11874410-Male,
pubmed-meshheading:11874410-Middle Aged
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pubmed:year |
2002
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pubmed:articleTitle |
Effects of low-dose oral hydrocortisone replacement versus short-term reproduction of physiological serum cortisol concentrations on insulin action in adult-onset hypopituitarism.
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pubmed:affiliation |
Sir George E. Clark Metabolic Unit and Regional Endocrine Laboratory, Royal Victoria Hospital, Belfast, UK.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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