rdf:type |
|
lifeskim:mentions |
umls-concept:C0001779,
umls-concept:C0009325,
umls-concept:C0026882,
umls-concept:C0029433,
umls-concept:C0043603,
umls-concept:C0087111,
umls-concept:C0205210,
umls-concept:C0332162,
umls-concept:C0439793,
umls-concept:C0681842,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1707520,
umls-concept:C2911692
|
pubmed:issue |
2
|
pubmed:dateCreated |
2002-3-4
|
pubmed:abstractText |
Severe forms of osteogenesis imperfecta (OI) are characterised by osteoporosis with multiple fractures, deformity, progressive loss of mobility and chronic bone pain. Bisphosphonates, as osteoclast inhibitors, reduce bone turnover and improve osteoporosis.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0334-018X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
163-74
|
pubmed:dateRevised |
2006-3-8
|
pubmed:meshHeading |
pubmed-meshheading:11874181-Adolescent,
pubmed-meshheading:11874181-Age Factors,
pubmed-meshheading:11874181-Bone Density,
pubmed-meshheading:11874181-Bone Remodeling,
pubmed-meshheading:11874181-Calcium,
pubmed-meshheading:11874181-Child,
pubmed-meshheading:11874181-Child, Preschool,
pubmed-meshheading:11874181-Collagen,
pubmed-meshheading:11874181-Collagen Type I,
pubmed-meshheading:11874181-Diphosphonates,
pubmed-meshheading:11874181-Humans,
pubmed-meshheading:11874181-Infant,
pubmed-meshheading:11874181-Kidney,
pubmed-meshheading:11874181-Mutation,
pubmed-meshheading:11874181-Osteogenesis Imperfecta,
pubmed-meshheading:11874181-Treatment Outcome
|
pubmed:year |
2002
|
pubmed:articleTitle |
Pamidronate treatment of osteogenesis imperfecta--lack of correlation between clinical severity, age at onset of treatment, predicted collagen mutation and treatment response.
|
pubmed:affiliation |
Department of Endocrinology and Diabetes, Royal Children's Hospital, Parkville, Victoria, Australia. zacharim@cryptic.rch.unimelb.edu.au
|
pubmed:publicationType |
Journal Article,
Clinical Trial
|