Source:http://linkedlifedata.com/resource/pubmed/id/11869364
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2002-2-28
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pubmed:abstractText |
The liver has emerged as an organ with distinct immunological properties. In this review, we summarize evidence that shows that the liver can remove apoptotic, or non-apoptotic but activated, CD8+ T cells from the circulation and induce apoptosis in these activated T cells by either active or passive mechanisms. Hepatitis viruses, particularly hepatitis C virus, often establish persistent infection. We review evidence that suggests that these viruses exploit intrahepatic tolerance mechanisms to protect themselves from immune attack.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0818-9641
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
80
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
74-83
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading | |
pubmed:year |
2002
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pubmed:articleTitle |
Biology and significance of T-cell apoptosis in the liver.
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pubmed:affiliation |
The David H Smith Center for VaccineBiology and Immunology, The University of Rochester, Rochester, New York 14642, USA.
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pubmed:publicationType |
Journal Article,
Review
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